Krüppel-like factor 3 inhibition by mutated lncRNA Reg1cp results in human high bone mass syndrome

High bone mass (HBM) is usually caused by gene mutations, and its mechanism remains unclear. In the present study, we identified a novel mutation in the long noncoding RNA Reg1cp that is associated with HBM. Subsequent analysis in 1,465 Chinese subjects revealed that heterozygous Reg1cp individuals...

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Detalles Bibliográficos
Autores principales: Yang, Mi, Guo, Qi, Peng, Hui, Xiao, Yu-Zhong, Xiao, Ye, Huang, Yan, Li, Chang-Jun, Su, Tian, Zhang, Yun-Lin, Lei, Min-Xiang, Chen, Hui-Ling, Jiang, Tie-Jian, Luo, Xiang-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683986/
https://www.ncbi.nlm.nih.gov/pubmed/31196982
http://dx.doi.org/10.1084/jem.20181554

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