Mg(2+) regulation of kinase signaling and immune function

Mg(2+) is required at micromolar concentrations as a cofactor for ATP, enzymatic reactions, and other biological processes. We show that decreased extracellular Mg(2+) reduced intracellular Mg(2+) levels and impaired the Ca(2+) flux, activation marker up-regulation, and proliferation after T cell re...

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Detalles Bibliográficos
Autores principales: Kanellopoulou, Chryssa, George, Alex B., Masutani, Evan, Cannons, Jennifer L., Ravell, Juan C., Yamamoto, Tori N., Smelkinson, Margery G., Jiang, Ping Du, Matsuda-Lennikov, Mami, Reilley, Julie, Handon, Robin, Lee, Ping-Hsien, Miller, J. Richard, Restifo, Nicholas P., Zheng, Lixin, Schwartzberg, Pamela L., Young, Matthew, Lenardo, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683994/
https://www.ncbi.nlm.nih.gov/pubmed/31196981
http://dx.doi.org/10.1084/jem.20181970

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