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C3- and CR3-dependent microglial clearance protects photoreceptors in retinitis pigmentosa
Complement activation has been implicated as contributing to neurodegeneration in retinal and brain pathologies, but its role in retinitis pigmentosa (RP), an inherited and largely incurable photoreceptor degenerative disease, is unclear. We found that multiple complement components were markedly up...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683998/ https://www.ncbi.nlm.nih.gov/pubmed/31209071 http://dx.doi.org/10.1084/jem.20190009 |