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The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors

CMVs efficiently target MHC I molecules to avoid recognition by cytotoxic T cells. However, the lack of MHC I on the cell surface renders the infected cell susceptible to NK cell killing upon missing self recognition. To counter this, mouse CMV (MCMV) rescues some MHC I molecules to engage inhibitor...

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Detalles Bibliográficos
Autores principales:	Železnjak, Jelena, Lisnić, Vanda Juranić, Popović, Branka, Lisnić, Berislav, Babić, Marina, Halenius, Anne, L’Hernault, Anne, Roviš, Tihana Lenac, Hengel, Hartmut, Erhard, Florian, Redwood, Alec J., Vidal, Silvia M., Dölken, Lars, Krmpotić, Astrid, Jonjić, Stipan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683999/ https://www.ncbi.nlm.nih.gov/pubmed/31142589 http://dx.doi.org/10.1084/jem.20182213

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