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Connecting signaling and metabolic pathways in EGF receptor-mediated oncogenesis of glioblastoma
As malignant transformation requires synchronization of growth-driving signaling (S) and metabolic (M) pathways, defining cancer-specific S-M interconnected networks (SMINs) could lead to better understanding of oncogenic processes. In a systems-biology approach, we developed a mathematical model fo...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684045/ https://www.ncbi.nlm.nih.gov/pubmed/31386654 http://dx.doi.org/10.1371/journal.pcbi.1007090 |