Cargando…

Relationship between the stage of osteoarthritis before and six months after tibial tuberosity advancement procedure in dogs

The present retrospective study evaluated the progression of osteoarthritis in stifle joints based on the radiographic grade of osteoarthritis (OA) scored in dogs with cranial cruciate ligament rupture. The aim of the study was to search for a correlation between the stage of radiographic osteoarthr...

Descripción completa

Detalles Bibliográficos
Autores principales: Pinna, Stefania, Lanzi, Francesco, Cordella, Alessia, Diana, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684061/
https://www.ncbi.nlm.nih.gov/pubmed/31386673
http://dx.doi.org/10.1371/journal.pone.0219849
_version_ 1783442206769545216
author Pinna, Stefania
Lanzi, Francesco
Cordella, Alessia
Diana, Alessia
author_facet Pinna, Stefania
Lanzi, Francesco
Cordella, Alessia
Diana, Alessia
author_sort Pinna, Stefania
collection PubMed
description The present retrospective study evaluated the progression of osteoarthritis in stifle joints based on the radiographic grade of osteoarthritis (OA) scored in dogs with cranial cruciate ligament rupture. The aim of the study was to search for a correlation between the stage of radiographic osteoarthritis prior to surgery and the osteoarthritis progression occurring after the tibial tuberosity advancement (TTA) procedure. It was hypothesized that the procedure carried out in dogs in the early stages of OA could reduce the OA changes. A total of 190 X-ray images obtained from the medical records of 38 dogs were evaluated. The radiographic signs of osteoarthritis of 38 stifle joints were scored from 0 to 3 in 10 specific anatomic locations. The radiographs were divided into 4 groups based on the global scores: A) no-OA, B) mild-OA, C) moderate-OA, D) severe-OA; they were assessed prior to surgery, and 1, 2, 3 and 6 months post-operatively (T0, T1, T2, T3 and T6). There were no differences in osteoarthritis progression in Groups A and C at any time. Osteoarthritis changes from T0 to T6 were statistically significant in Group B. The OA changes in the anatomic locations were investigated. The most common anatomic sites for OA changes were the patella apex, the proximal and distal trochlear ridges, and the caudal aspect of the tibial plateau assessed before surgery. After surgery, the score increased in the first three locations in 10, 9 and 11 joints, respectively; instead, the progression of osteoarthritis in the caudal aspect of the tibial plateau occurred in 23 out of 38 stifle joints. The results indicated that the TTA procedure could be effective in slowing down the OA progression when carried out in the absence of or in the early stages of disease. Therefore, an early intervention may be suggested in clinical practice to obtain minimal or no progression 6 months postoperatively.
format Online
Article
Text
id pubmed-6684061
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-66840612019-08-15 Relationship between the stage of osteoarthritis before and six months after tibial tuberosity advancement procedure in dogs Pinna, Stefania Lanzi, Francesco Cordella, Alessia Diana, Alessia PLoS One Research Article The present retrospective study evaluated the progression of osteoarthritis in stifle joints based on the radiographic grade of osteoarthritis (OA) scored in dogs with cranial cruciate ligament rupture. The aim of the study was to search for a correlation between the stage of radiographic osteoarthritis prior to surgery and the osteoarthritis progression occurring after the tibial tuberosity advancement (TTA) procedure. It was hypothesized that the procedure carried out in dogs in the early stages of OA could reduce the OA changes. A total of 190 X-ray images obtained from the medical records of 38 dogs were evaluated. The radiographic signs of osteoarthritis of 38 stifle joints were scored from 0 to 3 in 10 specific anatomic locations. The radiographs were divided into 4 groups based on the global scores: A) no-OA, B) mild-OA, C) moderate-OA, D) severe-OA; they were assessed prior to surgery, and 1, 2, 3 and 6 months post-operatively (T0, T1, T2, T3 and T6). There were no differences in osteoarthritis progression in Groups A and C at any time. Osteoarthritis changes from T0 to T6 were statistically significant in Group B. The OA changes in the anatomic locations were investigated. The most common anatomic sites for OA changes were the patella apex, the proximal and distal trochlear ridges, and the caudal aspect of the tibial plateau assessed before surgery. After surgery, the score increased in the first three locations in 10, 9 and 11 joints, respectively; instead, the progression of osteoarthritis in the caudal aspect of the tibial plateau occurred in 23 out of 38 stifle joints. The results indicated that the TTA procedure could be effective in slowing down the OA progression when carried out in the absence of or in the early stages of disease. Therefore, an early intervention may be suggested in clinical practice to obtain minimal or no progression 6 months postoperatively. Public Library of Science 2019-08-06 /pmc/articles/PMC6684061/ /pubmed/31386673 http://dx.doi.org/10.1371/journal.pone.0219849 Text en © 2019 Pinna et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Pinna, Stefania
Lanzi, Francesco
Cordella, Alessia
Diana, Alessia
Relationship between the stage of osteoarthritis before and six months after tibial tuberosity advancement procedure in dogs
title Relationship between the stage of osteoarthritis before and six months after tibial tuberosity advancement procedure in dogs
title_full Relationship between the stage of osteoarthritis before and six months after tibial tuberosity advancement procedure in dogs
title_fullStr Relationship between the stage of osteoarthritis before and six months after tibial tuberosity advancement procedure in dogs
title_full_unstemmed Relationship between the stage of osteoarthritis before and six months after tibial tuberosity advancement procedure in dogs
title_short Relationship between the stage of osteoarthritis before and six months after tibial tuberosity advancement procedure in dogs
title_sort relationship between the stage of osteoarthritis before and six months after tibial tuberosity advancement procedure in dogs
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684061/
https://www.ncbi.nlm.nih.gov/pubmed/31386673
http://dx.doi.org/10.1371/journal.pone.0219849
work_keys_str_mv AT pinnastefania relationshipbetweenthestageofosteoarthritisbeforeandsixmonthsaftertibialtuberosityadvancementprocedureindogs
AT lanzifrancesco relationshipbetweenthestageofosteoarthritisbeforeandsixmonthsaftertibialtuberosityadvancementprocedureindogs
AT cordellaalessia relationshipbetweenthestageofosteoarthritisbeforeandsixmonthsaftertibialtuberosityadvancementprocedureindogs
AT dianaalessia relationshipbetweenthestageofosteoarthritisbeforeandsixmonthsaftertibialtuberosityadvancementprocedureindogs