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IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses

Despite existing evidence for tuning of innate immunity to different classes of bacteria, the molecular mechanisms used by macrophages to tailor inflammatory responses to specific pathogens remain incompletely defined. By stimulating mouse macrophages with a titration matrix of TLR ligand pairs, we...

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Detalles Bibliográficos
Autores principales:	Gottschalk, Rachel A, Dorrington, Michael G, Dutta, Bhaskar, Krauss, Kathleen S, Martins, Andrew J, Uderhardt, Stefan, Chan, Waipan, Tsang, John S, Torabi-Parizi, Parizad, Fraser, Iain DC, Germain, Ronald N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684266/ https://www.ncbi.nlm.nih.gov/pubmed/31385572 http://dx.doi.org/10.7554/eLife.46836

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