A Rare Case of Syndrome of Inappropriate Anti-diuretic Hormone in Non-small Cell Lung Cancer Presenting as Superior Vena Cava Syndrome

Syndrome of inappropriate anti-diuretic hormone (SIADH) secretion is uncommon in small cell lung cancer (SCLC), but even more rare in cases of non-small cell lung cancer (NSCLC). We report a case of a 59-year-old male who presented with superior vena cava (SVC) syndrome. After further investigation,...

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Autores principales: Ishihara, Rhys, Stoos, Catherine, Jagadesh, Sunil, Nguyen, Cam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Radiation Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684297/
https://www.ncbi.nlm.nih.gov/pubmed/31410343
http://dx.doi.org/10.7759/cureus.4861
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author Ishihara, Rhys
Stoos, Catherine
Jagadesh, Sunil
Nguyen, Cam
author_facet Ishihara, Rhys
Stoos, Catherine
Jagadesh, Sunil
Nguyen, Cam
author_sort Ishihara, Rhys
collection PubMed
description Syndrome of inappropriate anti-diuretic hormone (SIADH) secretion is uncommon in small cell lung cancer (SCLC), but even more rare in cases of non-small cell lung cancer (NSCLC). We report a case of a 59-year-old male who presented with superior vena cava (SVC) syndrome. After further investigation, he was diagnosed with adenocarcinoma of the lung. He delayed his medical care and his condition worsened. He was diagnosed with SIADH as an incidental finding on routine lab draw. Radiotherapy was subsequently initiated, and after one week of treatment, the patient showed marked clinical improvement. In this article, we also review the current indications for radiotherapy in various lung cancers and the management of SIADH.
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spelling pubmed-66842972019-08-13 A Rare Case of Syndrome of Inappropriate Anti-diuretic Hormone in Non-small Cell Lung Cancer Presenting as Superior Vena Cava Syndrome Ishihara, Rhys Stoos, Catherine Jagadesh, Sunil Nguyen, Cam Cureus Radiation Oncology Syndrome of inappropriate anti-diuretic hormone (SIADH) secretion is uncommon in small cell lung cancer (SCLC), but even more rare in cases of non-small cell lung cancer (NSCLC). We report a case of a 59-year-old male who presented with superior vena cava (SVC) syndrome. After further investigation, he was diagnosed with adenocarcinoma of the lung. He delayed his medical care and his condition worsened. He was diagnosed with SIADH as an incidental finding on routine lab draw. Radiotherapy was subsequently initiated, and after one week of treatment, the patient showed marked clinical improvement. In this article, we also review the current indications for radiotherapy in various lung cancers and the management of SIADH. Cureus 2019-06-07 /pmc/articles/PMC6684297/ /pubmed/31410343 http://dx.doi.org/10.7759/cureus.4861 Text en Copyright © 2019, Ishihara et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiation Oncology
Ishihara, Rhys
Stoos, Catherine
Jagadesh, Sunil
Nguyen, Cam
A Rare Case of Syndrome of Inappropriate Anti-diuretic Hormone in Non-small Cell Lung Cancer Presenting as Superior Vena Cava Syndrome
title A Rare Case of Syndrome of Inappropriate Anti-diuretic Hormone in Non-small Cell Lung Cancer Presenting as Superior Vena Cava Syndrome
title_full A Rare Case of Syndrome of Inappropriate Anti-diuretic Hormone in Non-small Cell Lung Cancer Presenting as Superior Vena Cava Syndrome
title_fullStr A Rare Case of Syndrome of Inappropriate Anti-diuretic Hormone in Non-small Cell Lung Cancer Presenting as Superior Vena Cava Syndrome
title_full_unstemmed A Rare Case of Syndrome of Inappropriate Anti-diuretic Hormone in Non-small Cell Lung Cancer Presenting as Superior Vena Cava Syndrome
title_short A Rare Case of Syndrome of Inappropriate Anti-diuretic Hormone in Non-small Cell Lung Cancer Presenting as Superior Vena Cava Syndrome
title_sort rare case of syndrome of inappropriate anti-diuretic hormone in non-small cell lung cancer presenting as superior vena cava syndrome
topic Radiation Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684297/
https://www.ncbi.nlm.nih.gov/pubmed/31410343
http://dx.doi.org/10.7759/cureus.4861
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