On inotropic effects of UTP in the human heart

Uridine 5′-triphosphate (UTP) exerts a positive inotropic effect (PIE) in isolated electrically driven isolated right atrial trabeculae carneae from patients undergoing heart surgery. This review discusses some aspects of the current knowledge on the putative receptor(s) involved and the potential b...

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Detalles Bibliográficos
Autores principales: Neumann, J., Hofmann, B., Gergs, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684494/
https://www.ncbi.nlm.nih.gov/pubmed/31406941
http://dx.doi.org/10.1016/j.heliyon.2019.e02197
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author Neumann, J.
Hofmann, B.
Gergs, U.
author_facet Neumann, J.
Hofmann, B.
Gergs, U.
author_sort Neumann, J.
collection PubMed
description Uridine 5′-triphosphate (UTP) exerts a positive inotropic effect (PIE) in isolated electrically driven isolated right atrial trabeculae carneae from patients undergoing heart surgery. This review discusses some aspects of the current knowledge on the putative receptor(s) involved and the potential biochemical transduction steps leading to the PIE.
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spelling pubmed-66844942019-08-12 On inotropic effects of UTP in the human heart Neumann, J. Hofmann, B. Gergs, U. Heliyon Article Uridine 5′-triphosphate (UTP) exerts a positive inotropic effect (PIE) in isolated electrically driven isolated right atrial trabeculae carneae from patients undergoing heart surgery. This review discusses some aspects of the current knowledge on the putative receptor(s) involved and the potential biochemical transduction steps leading to the PIE. Elsevier 2019-08-02 /pmc/articles/PMC6684494/ /pubmed/31406941 http://dx.doi.org/10.1016/j.heliyon.2019.e02197 Text en © 2019 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Neumann, J.
Hofmann, B.
Gergs, U.
On inotropic effects of UTP in the human heart
title On inotropic effects of UTP in the human heart
title_full On inotropic effects of UTP in the human heart
title_fullStr On inotropic effects of UTP in the human heart
title_full_unstemmed On inotropic effects of UTP in the human heart
title_short On inotropic effects of UTP in the human heart
title_sort on inotropic effects of utp in the human heart
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684494/
https://www.ncbi.nlm.nih.gov/pubmed/31406941
http://dx.doi.org/10.1016/j.heliyon.2019.e02197
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