Cargando…
Histone chaperone exploits intrinsic disorder to switch acetylation specificity
Histones, the principal protein components of chromatin, contain long disordered sequences, which are extensively post-translationally modified. Although histone chaperones are known to control both the activity and specificity of histone-modifying enzymes, the mechanisms promoting modification of h...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684614/ https://www.ncbi.nlm.nih.gov/pubmed/31387991 http://dx.doi.org/10.1038/s41467-019-11410-7 |