Regional mitochondrial DNA and cell-type changes in post-mortem brains of non-diabetic Alzheimer’s disease are not present in diabetic Alzheimer’s disease

Diabetes increases the risk of Alzheimer’s disease (AD), and mitochondrial dysfunction is implicated in both diseases, however the impact of both diabetes and AD on brain mitochondria is not known. We measured mitochondrial DNA (mtDNA), an indicator of mitochondrial function, in frontal, parietal, a...

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Detalles Bibliográficos
Autores principales: Thubron, Elisabeth B., Rosa, Hannah S., Hodges, Angela, Sivaprasad, Sobha, Francis, Paul T., Pienaar, Ilse S., Malik, Afshan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684616/
https://www.ncbi.nlm.nih.gov/pubmed/31388037
http://dx.doi.org/10.1038/s41598-019-47783-4

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