Cargando…
Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study
Metabolomics is an emerging science that can inform pathogenic mechanisms behind clinical phenotypes in COPD. We aimed to understand disturbances in the serum metabolome associated with respiratory outcomes in ever-smokers from the SPIROMICS cohort. We measured 27 serum metabolites, mostly amino aci...
Autores principales: | Labaki, Wassim W., Gu, Tian, Murray, Susan, Curtis, Jeffrey L., Yeomans, Larisa, Bowler, Russell P., Barr, R. Graham, Comellas, Alejandro P., Hansel, Nadia N., Cooper, Christopher B., Barjaktarevic, Igor, Kanner, Richard E., Paine, Robert, McDonald, Merry-Lynn N., Krishnan, Jerry A., Peters, Stephen P., Woodruff, Prescott G., O’Neal, Wanda K., Diao, Wenqi, He, Bei, Martinez, Fernando J., Standiford, Theodore J., Stringer, Kathleen A., Han, MeiLan K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684630/ https://www.ncbi.nlm.nih.gov/pubmed/31388056 http://dx.doi.org/10.1038/s41598-019-47761-w |
Ejemplares similares
-
Association of thrombocytosis with COPD morbidity: the SPIROMICS and COPDGene cohorts
por: Fawzy, Ashraf, et al.
Publicado: (2018) -
Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS
por: Putcha, Nirupama, et al.
Publicado: (2018) -
Frequency of Exacerbations in COPD: An Analysis of the SPIROMICS Cohort
por: Han, MeiLan K., et al.
Publicado: (2017) -
Novel Respiratory Disability Score Predicts COPD Exacerbations and Mortality in the SPIROMICS Cohort
por: Cooper, Christopher B, et al.
Publicado: (2020) -
Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort
por: Zhang, William Z., et al.
Publicado: (2021)