Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways

The synaptotagmin (syt) proteins have been widely studied for their role in regulating fusion of intracellular vesicles with the plasma membrane. Here we report that syt-17, an unusual isoform of unknown function, plays no role in exocytosis, and instead plays multiple roles in intracellular membran...

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Detalles Bibliográficos
Autores principales: Ruhl, David A., Bomba-Warczak, Ewa, Watson, Emma T., Bradberry, Mazdak M., Peterson, Tabitha A., Basu, Trina, Frelka, Alyssa, Evans, Chantell S., Briguglio, Joseph S., Basta, Tamara, Stowell, Michael H. B., Savas, Jeffrey N., Roopra, Avtar, Pearce, Robert A., Piper, Robert C., Chapman, Edwin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684635/
https://www.ncbi.nlm.nih.gov/pubmed/31387992
http://dx.doi.org/10.1038/s41467-019-11459-4

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