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Pancreatic (pro)enzymes treatment suppresses BXPC-3 pancreatic Cancer Stem Cell subpopulation and impairs tumour engrafting

Cancer stem cells (CSCs) subpopulation within the tumour is responsible for metastasis and cancer relapse. Here we investigate in vitro and in vivo the effects of a pancreatic (pro)enzyme mixture composed of Chymotrypsinogen and Trypsinogen (PRP) on CSCs derived from a human pancreatic cell line, Bx...

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Detalles Bibliográficos
Autores principales:	Hernández-Camarero, Pablo, López-Ruiz, Elena, Griñán-Lisón, Carmen, García, María Ángel, Chocarro-Wrona, Carlos, Marchal, Juan Antonio, Kenyon, Julian, Perán, Macarena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684636/ https://www.ncbi.nlm.nih.gov/pubmed/31388092 http://dx.doi.org/10.1038/s41598-019-47837-7

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