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Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export

The intracellular transport of cholesterol is subject to tight regulation. The structure of the lysosomal integral membrane protein type 2 (LIMP-2, also known as SCARB2) reveals a large cavity that traverses the molecule and resembles the cavity in SR-B1 that mediates lipid transfer. The detection o...

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Detalles Bibliográficos
Autores principales:	Heybrock, Saskia, Kanerva, Kristiina, Meng, Ying, Ing, Chris, Liang, Anna, Xiong, Zi-Jian, Weng, Xialian, Ah Kim, Young, Collins, Richard, Trimble, William, Pomès, Régis, Privé, Gilbert G., Annaert, Wim, Schwake, Michael, Heeren, Joerg, Lüllmann-Rauch, Renate, Grinstein, Sergio, Ikonen, Elina, Saftig, Paul, Neculai, Dante
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684646/ https://www.ncbi.nlm.nih.gov/pubmed/31387993 http://dx.doi.org/10.1038/s41467-019-11425-0

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