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Single T Cell Sequencing Demonstrates the Functional Role of αβ TCR Pairing in Cell Lineage and Antigen Specificity

Although structural studies of individual T cell receptors (TCRs) have revealed important roles for both the α and β chain in directing MHC and antigen recognition, repertoire-level immunogenomic analyses have historically examined the β chain alone. To determine the amount of useful information abo...

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Detalles Bibliográficos
Autores principales:	Carter, Jason A., Preall, Jonathan B., Grigaityte, Kristina, Goldfless, Stephen J., Jeffery, Eric, Briggs, Adrian W., Vigneault, Francois, Atwal, Gurinder S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684766/ https://www.ncbi.nlm.nih.gov/pubmed/31417541 http://dx.doi.org/10.3389/fimmu.2019.01516

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