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Unveiling the gene regulatory landscape in diseases through the identification of DNase I-hypersensitive sites
DNase I-hypersensitive sites (DHSs) serve key roles in the regulation of gene transcription as markers of cis-regulatory elements (CREs). Recent advances in next-generation sequencing have enabled the genome-wide location and annotation of DHSs in a variety of cells. Numerous studies have confirmed...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684942/ https://www.ncbi.nlm.nih.gov/pubmed/31423302 http://dx.doi.org/10.3892/br.2019.1233 |