Cargando…

Identification of an oncogenic network with prognostic and therapeutic value in prostate cancer

Identifying critical pathways governing disease progression is essential for accurate prognosis and effective therapy. We developed a broadly applicable and novel systems‐level gene discovery strategy. This approach focused on constitutively active androgen receptor (AR) splice variant‐driven pathwa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Magani, Fiorella, Bray, Eric R, Martinez, Maria J, Zhao, Ning, Copello, Valeria A, Heidman, Laine, Peacock, Stephanie O, Wiley, David J, D'Urso, Gennaro, Burnstein, Kerry L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684952/ https://www.ncbi.nlm.nih.gov/pubmed/30108134 http://dx.doi.org/10.15252/msb.20188202

Ejemplares similares

The kinesin KIF20A promotes progression to castration-resistant prostate cancer through autocrine activation of the androgen receptor
por: Copello, Valeria A., et al.
Publicado: (2022)

Reduced Arginyltransferase 1 is a driver and a potential prognostic indicator of prostate cancer metastasis
por: Birnbaum, Michael D., et al.
Publicado: (2018)

Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo
por: Wiley, David J., et al.
Publicado: (2020)

The Prognostic Value of DCE-MRI Findings before Salvage Radiotherapy after Radical Prostatectomy
por: Farneti, Alessia, et al.
Publicado: (2023)

Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases
por: Wiley, David J., et al.
Publicado: (2014)

Functional characterizations of rare UBA1 variants in X-linked Spinal Muscular Atrophy
por: Balak, Chris D., et al.
Publicado: (2017)

A genetic screen for replication initiation defective (rid) mutants in Schizosaccharomyces pombe
por: Locovei, Alexandra M, et al.
Publicado: (2010)

Is androgen receptor activity in metastatic prostate cancer a good biomarker for bipolar androgen therapy?
por: Peinetti, Nahuel, et al.
Publicado: (2022)

Cdc42 GTPase-activating proteins (GAPs) regulate generational inheritance of cell polarity and cell shape in fission yeast
por: Pino, Marbelys Rodriguez, et al.
Publicado: (2021)

Some Account of a New Theory of Galvanic Electricity, Founded on Experiments
por: Heidman, M. J. A.
Publicado: (1807)

miR-15b and miR-21 as Circulating Biomarkers for Diagnosis of Glioma
por: Ivo D’Urso, Pietro, et al.
Publicado: (2015)

A novel calcium-dependent mechanism of acquired resistance to IGF-1 receptor inhibition in prostate cancer cells
por: Fahrenholtz, Cale D, et al.
Publicado: (2014)

Role of PhaC Type I and Type II Enzymes during PHA Biosynthesis
por: Mezzolla, Valeria, et al.
Publicado: (2018)

Automation, live-cell imaging, and endpoint cell viability for prostate cancer drug screens
por: Lyles, Rolando D. Z., et al.
Publicado: (2023)

Efficient proximal gradient algorithm for inference of differential gene networks
por: Wang, Chen, et al.
Publicado: (2019)

DAMPE: A gamma and cosmic ray observatory in space
por: D'Urso, D
Publicado: (2017)

Inhibition of the serine/threonine kinase BUB1 reverses taxane resistance in prostate cancer
por: Martinez, Maria J., et al.
Publicado: (2023)

Refinement & validation of rectal wall dose volume objectives for prostate hypofractionation in 20 fractions
por: Sanguineti, Giuseppe, et al.
Publicado: (2020)

A prospective study assessing the pattern of response of local disease at DCE-MRI after salvage radiotherapy for prostate cancer()
por: Bottero, Marta, et al.
Publicado: (2022)

SYDE1 Acts as an Oncogene in Glioma and has Diagnostic and Prognostic Values
por: Han, Zhenyuan, et al.
Publicado: (2021)

Cadherin‐3 is a novel oncogenic biomarker with prognostic value in glioblastoma
por: Martins, Eduarda P., et al.
Publicado: (2022)

The CENP-B homolog, Abp1, interacts with the initiation protein Cdc23 (MCM10) and is required for efficient DNA replication in fission yeast
por: Locovei, Alexandra M, et al.
Publicado: (2006)

The microRNA -23b/-27b Cluster Suppresses the Metastatic Phenotype of Castration-Resistant Prostate Cancer Cells
por: Ishteiwy, Reema A., et al.
Publicado: (2012)

Minimally invasive posterior fossa decompression in Chiari I malformation
por: D’Urso, Pietro Ivo
Publicado: (2019)

Thermo-Mechanical Characterization of Friction Stir Spot Welded AA7050 Sheets by Means of Experimental and FEM Analyses
por: D’Urso, Gianluca, et al.
Publicado: (2016)

Special Issue of Materials focusing on “Finite Element Analysis and Models of Sustainable Manufacturing Processes”
por: Giardini, Claudio, et al.
Publicado: (2022)

A Novel Nuclear Role for the Vav3 Nucleotide Exchange Factor in Androgen Receptor Coactivation in Prostate Cancer
por: Rao, Shuyun, et al.
Publicado: (2011)

Convexity meningioma associated with noncontiguous dural arteriovenous fistula
por: Manzo, Marco, et al.
Publicado: (2020)

Craniocervical junction arachnoid cyst
por: Manzo, Marco, et al.
Publicado: (2020)

Mechanical and Physical Regulation of Fibroblast–Myofibroblast Transition: From Cellular Mechanoresponse to Tissue Pathology
por: D'Urso, Mirko, et al.
Publicado: (2020)

New Insights into Polygenic Score–Lifestyle Interactions for Cardiometabolic Risk Factors from Genome-Wide Interaction Analyses
por: D’Urso, Shannon, et al.
Publicado: (2023)

Ovarian dysfunction and FMR1 alleles in a large Italian family with POF and FRAXA disorders: case report
por: Miano, Maria Giuseppina, et al.
Publicado: (2007)

Oncogenic mutations are associated with histological subtypes but do not have an independent prognostic value in lung adenocarcinoma
por: Hu, Haichuan, et al.
Publicado: (2014)

Oncogenic Role and Prognostic Value of MicroRNA-937-3p in Patients with Breast Cancer
por: Li, Deyu, et al.
Publicado: (2019)

Prognostic Value of Erythroblastic Leukemia Viral Oncogene Homolog 2 and Neuregulin 4 in Hepatocellular Carcinoma
por: Rou, Woo Sun, et al.
Publicado: (2023)

International Conference on Earth Observation for Vegetation Monitoring and Water Mangement
por: D'Urso, G, et al.
Publicado: (2006)

Prognostic value of genomic mutations in metastatic prostate cancer()()
por: Zhu, Honghui, et al.
Publicado: (2023)

The long tail of oncogenic drivers in prostate cancer
por: Armenia, Joshua, et al.
Publicado: (2018)

Study on ZrB(2)-Based Ceramics Reinforced with SiC Fibers or Whiskers Machined by Micro-Electrical Discharge Machining
por: Quarto, Mariangela, et al.
Publicado: (2020)

The Vicissitudes of Homophobic Victimization in Adolescence: An Explorative Study
por: Pace, Ugo, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rjvuho538l4ni0fsa0noc9mjf2