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Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens
Syphilis, caused by Treponema pallidum subsp. pallidum (TPA), remains an important public health problem with an increasing worldwide prevalence. Despite recent advances in in vitro cultivation, genetic variability of this pathogen during infection is poorly understood. Here, we present contemporary...
Autores principales: | Grillová, Linda, Oppelt, Jan, Mikalová, Lenka, Nováková, Markéta, Giacani, Lorenzo, Niesnerová, Anežka, Noda, Angel A., Mechaly, Ariel E., Pospíšilová, Petra, Čejková, Darina, Grange, Philippe A., Dupin, Nicolas, Strnadel, Radim, Chen, Marcus, Denham, Ian, Arora, Natasha, Picardeau, Mathieu, Weston, Christopher, Forsyth, R. Allyn, Šmajs, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685089/ https://www.ncbi.nlm.nih.gov/pubmed/31417509 http://dx.doi.org/10.3389/fmicb.2019.01691 |
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