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Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens

Syphilis, caused by Treponema pallidum subsp. pallidum (TPA), remains an important public health problem with an increasing worldwide prevalence. Despite recent advances in in vitro cultivation, genetic variability of this pathogen during infection is poorly understood. Here, we present contemporary...

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Detalles Bibliográficos
Autores principales: Grillová, Linda, Oppelt, Jan, Mikalová, Lenka, Nováková, Markéta, Giacani, Lorenzo, Niesnerová, Anežka, Noda, Angel A., Mechaly, Ariel E., Pospíšilová, Petra, Čejková, Darina, Grange, Philippe A., Dupin, Nicolas, Strnadel, Radim, Chen, Marcus, Denham, Ian, Arora, Natasha, Picardeau, Mathieu, Weston, Christopher, Forsyth, R. Allyn, Šmajs, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685089/
https://www.ncbi.nlm.nih.gov/pubmed/31417509
http://dx.doi.org/10.3389/fmicb.2019.01691

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