Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice

BACKGROUND: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a sometimes life-threatening complication in RA patients. SKG mice develop not only arthritis but also an ILD resembling RA-ILD. We previously reported that tofacitinib, a JAK inhibitor, facilitates the expansion of my...

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Detalles Bibliográficos
Autores principales: Sendo, Sho, Saegusa, Jun, Yamada, Hirotaka, Nishimura, Keisuke, Morinobu, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685227/
https://www.ncbi.nlm.nih.gov/pubmed/31387650
http://dx.doi.org/10.1186/s13075-019-1963-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685227/
https://www.ncbi.nlm.nih.gov/pubmed/31387650
http://dx.doi.org/10.1186/s13075-019-1963-2

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