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Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice
BACKGROUND: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a sometimes life-threatening complication in RA patients. SKG mice develop not only arthritis but also an ILD resembling RA-ILD. We previously reported that tofacitinib, a JAK inhibitor, facilitates the expansion of my...
Autores principales: | Sendo, Sho, Saegusa, Jun, Yamada, Hirotaka, Nishimura, Keisuke, Morinobu, Akio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685227/ https://www.ncbi.nlm.nih.gov/pubmed/31387650 http://dx.doi.org/10.1186/s13075-019-1963-2 |
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