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A case report of successfully treated nephrotic syndrome after renal angioplasty

BACKGROUND: The standard treatment of renovascular hypertension accompanying renal artery stenosis (RAS) consists of angioplasty and administration of antihypertensive medication. Although nephrotic syndrome (NS) has been reported to be associated with RAS, the development of NS after revascularizat...

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Autores principales: Park, Hee Jung, Jang, Ha Nee, Cho, Hyun Seop, Chang, Se-Ho, Kim, Hyun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685235/
https://www.ncbi.nlm.nih.gov/pubmed/31387536
http://dx.doi.org/10.1186/s12882-019-1503-y
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author Park, Hee Jung
Jang, Ha Nee
Cho, Hyun Seop
Chang, Se-Ho
Kim, Hyun-Jung
author_facet Park, Hee Jung
Jang, Ha Nee
Cho, Hyun Seop
Chang, Se-Ho
Kim, Hyun-Jung
author_sort Park, Hee Jung
collection PubMed
description BACKGROUND: The standard treatment of renovascular hypertension accompanying renal artery stenosis (RAS) consists of angioplasty and administration of antihypertensive medication. Although nephrotic syndrome (NS) has been reported to be associated with RAS, the development of NS after revascularization of RAS is extremely rare. CASE PRESENTATION: A 48-year-old man presented with uncontrolled hypertension and azotemia. The right kidney was atrophic, and RAS of the left kidney was suspected based on a post-captopril DTPA scan. His blood pressure stabilized after renal angioplasty; however, he complained of edema after 1 week. NS developed and was diagnosed as focal segmental glomerulosclerosis (FSGS) based on renal biopsy. He received an angiotensin receptor blocker. Proteinuria resolved after 1 year. CONCLUSIONS: FSGS rarely develops after angioplasty of renal artery stenosis. This is the first report of successful treatment of this condition using an angiotensin receptor blocker during 1-year follow-up.
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spelling pubmed-66852352019-08-12 A case report of successfully treated nephrotic syndrome after renal angioplasty Park, Hee Jung Jang, Ha Nee Cho, Hyun Seop Chang, Se-Ho Kim, Hyun-Jung BMC Nephrol Case Report BACKGROUND: The standard treatment of renovascular hypertension accompanying renal artery stenosis (RAS) consists of angioplasty and administration of antihypertensive medication. Although nephrotic syndrome (NS) has been reported to be associated with RAS, the development of NS after revascularization of RAS is extremely rare. CASE PRESENTATION: A 48-year-old man presented with uncontrolled hypertension and azotemia. The right kidney was atrophic, and RAS of the left kidney was suspected based on a post-captopril DTPA scan. His blood pressure stabilized after renal angioplasty; however, he complained of edema after 1 week. NS developed and was diagnosed as focal segmental glomerulosclerosis (FSGS) based on renal biopsy. He received an angiotensin receptor blocker. Proteinuria resolved after 1 year. CONCLUSIONS: FSGS rarely develops after angioplasty of renal artery stenosis. This is the first report of successful treatment of this condition using an angiotensin receptor blocker during 1-year follow-up. BioMed Central 2019-08-06 /pmc/articles/PMC6685235/ /pubmed/31387536 http://dx.doi.org/10.1186/s12882-019-1503-y Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Park, Hee Jung
Jang, Ha Nee
Cho, Hyun Seop
Chang, Se-Ho
Kim, Hyun-Jung
A case report of successfully treated nephrotic syndrome after renal angioplasty
title A case report of successfully treated nephrotic syndrome after renal angioplasty
title_full A case report of successfully treated nephrotic syndrome after renal angioplasty
title_fullStr A case report of successfully treated nephrotic syndrome after renal angioplasty
title_full_unstemmed A case report of successfully treated nephrotic syndrome after renal angioplasty
title_short A case report of successfully treated nephrotic syndrome after renal angioplasty
title_sort case report of successfully treated nephrotic syndrome after renal angioplasty
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685235/
https://www.ncbi.nlm.nih.gov/pubmed/31387536
http://dx.doi.org/10.1186/s12882-019-1503-y
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