An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons

BACKGROUND: Brain microvascular endothelial cells (BMECs) astrocytes, neurons, and pericytes form the neurovascular unit (NVU). Interactions with NVU cells endow BMECs with extremely tight barriers via the expression of tight junction proteins, a host of active efflux and nutrient transporters, and...

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Detalles Bibliográficos
Autores principales: Canfield, Scott G., Stebbins, Matthew J., Faubion, Madeline G., Gastfriend, Benjamin D., Palecek, Sean P., Shusta, Eric V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685239/
https://www.ncbi.nlm.nih.gov/pubmed/31387594
http://dx.doi.org/10.1186/s12987-019-0145-6

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