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Depleting PTOV1 sensitizes non-small cell lung cancer cells to chemotherapy through attenuating cancer stem cell traits

BACKGROUND: Prostate tumor over expressed gene 1 (PTOV1) has been reported as an oncogene in several human cancers. However, the clinical significance and biological role of PTOV1 remain elusive in non-small cell lung cancer (NSCLC). METHODS: The Cancer Genome Atlas (TCGA) data and NCBI/GEO data min...

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Detalles Bibliográficos
Autores principales: Wu, Zhiqiang, Liu, Zhuang, Jiang, Xiangli, Mi, Zeyun, Meng, Maobin, Wang, Hui, Zhao, Jinlin, Zheng, Boyu, Yuan, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685258/
https://www.ncbi.nlm.nih.gov/pubmed/31387622
http://dx.doi.org/10.1186/s13046-019-1349-y