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Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury

We found differences related to the neuro-functional deficiency and clinical progress, among non-consumers and chronic consumers of ethanol, with recent traumatic spinal cord injury (SCI). We present a synthesis of related data on lesion mechanisms in post-traumatic myelogenous disorders, namely som...

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Autores principales: Stoica, Simona Isabelle, Tănase, Ioana, Ciobanu, Vlad, Onose, Gelu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685305/
https://www.ncbi.nlm.nih.gov/pubmed/31406510
http://dx.doi.org/10.25122/jml-2019-0026
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author Stoica, Simona Isabelle
Tănase, Ioana
Ciobanu, Vlad
Onose, Gelu
author_facet Stoica, Simona Isabelle
Tănase, Ioana
Ciobanu, Vlad
Onose, Gelu
author_sort Stoica, Simona Isabelle
collection PubMed
description We found differences related to the neuro-functional deficiency and clinical progress, among non-consumers and chronic consumers of ethanol, with recent traumatic spinal cord injury (SCI). We present a synthesis of related data on lesion mechanisms in post-traumatic myelogenous disorders, namely some of the alcohols and their actions on the nervous system, with details on the influences exerted, in such afflictions, by the chronic consumption of ethanol. The subject is not frequently approached – according to a literature review with systematic elements, which we have done before – thus constituting a niche that deserves to be further explored. The applicative component of the article highlights statistical data resulted from a retrospective study regarding the specialized casuistry from the Neuromuscular Recovery Clinic of the “Bagdasar Arseni” Emergency Clinical Hospital, following the comparative analysis of two groups of patients with recent SCI: non-consumers – the control group (n=780) – and chronic ethanol consumers – the study group (n=225) – with the addition of a prospective pilot component. Data processing has been achieved with SPSS 24. The American Spinal Injury Association Impairment Scale (AIS) mean motor scores differ significantly (tests: Mann-Whitney and t) between the control and study group in favor of the second, both at admission (p<0.001) and at discharge (p<0.001). AIS mean sensitive scores differ between the two lots, and also in favor of the study, but statistically significant only at discharge (p=0.048); the difference at admission is not significant (p=0.51) – possibly because of alcoholic-nutritional polyneuropathy. These findings, with numerous related details, later presented in the text, are surprising, which requires further studies and attempts of understanding.
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spelling pubmed-66853052019-08-12 Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury Stoica, Simona Isabelle Tănase, Ioana Ciobanu, Vlad Onose, Gelu J Med Life Review We found differences related to the neuro-functional deficiency and clinical progress, among non-consumers and chronic consumers of ethanol, with recent traumatic spinal cord injury (SCI). We present a synthesis of related data on lesion mechanisms in post-traumatic myelogenous disorders, namely some of the alcohols and their actions on the nervous system, with details on the influences exerted, in such afflictions, by the chronic consumption of ethanol. The subject is not frequently approached – according to a literature review with systematic elements, which we have done before – thus constituting a niche that deserves to be further explored. The applicative component of the article highlights statistical data resulted from a retrospective study regarding the specialized casuistry from the Neuromuscular Recovery Clinic of the “Bagdasar Arseni” Emergency Clinical Hospital, following the comparative analysis of two groups of patients with recent SCI: non-consumers – the control group (n=780) – and chronic ethanol consumers – the study group (n=225) – with the addition of a prospective pilot component. Data processing has been achieved with SPSS 24. The American Spinal Injury Association Impairment Scale (AIS) mean motor scores differ significantly (tests: Mann-Whitney and t) between the control and study group in favor of the second, both at admission (p<0.001) and at discharge (p<0.001). AIS mean sensitive scores differ between the two lots, and also in favor of the study, but statistically significant only at discharge (p=0.048); the difference at admission is not significant (p=0.51) – possibly because of alcoholic-nutritional polyneuropathy. These findings, with numerous related details, later presented in the text, are surprising, which requires further studies and attempts of understanding. Carol Davila University Press 2019 /pmc/articles/PMC6685305/ /pubmed/31406510 http://dx.doi.org/10.25122/jml-2019-0026 Text en ©Carol Davila University Press This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Review
Stoica, Simona Isabelle
Tănase, Ioana
Ciobanu, Vlad
Onose, Gelu
Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury
title Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury
title_full Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury
title_fullStr Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury
title_full_unstemmed Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury
title_short Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury
title_sort initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685305/
https://www.ncbi.nlm.nih.gov/pubmed/31406510
http://dx.doi.org/10.25122/jml-2019-0026
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