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Evaluation of Whole-Genome Sequence Method to Diagnose Resistance of 13 Anti-tuberculosis Drugs and Characterize Resistance Genes in Clinical Multi-Drug Resistance Mycobacterium tuberculosis Isolates From China
Background: Whole-genome sequencing (WGS) is a viable and financially feasible tool for timely and comprehensive diagnosis of drug resistance in developed countries. With the increase in the incidence of multidrug-resistant tuberculosis (MDR-TB), second-line anti-TB drugs are gaining importance. How...
Autores principales: | Chen, Xinchang, He, Guiqing, Wang, Shiyong, Lin, Siran, Chen, Jiazhen, Zhang, Wenhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685394/ https://www.ncbi.nlm.nih.gov/pubmed/31417530 http://dx.doi.org/10.3389/fmicb.2019.01741 |
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