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Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function

Dysfunction of the blood-brain barrier (BBB) contributes significantly to the pathogenesis of several neuroinflammatory diseases, including multiple sclerosis (MS). Potential players that regulate BBB function are the liver X receptors (LXRs), which are ligand activated transcription factors compris...

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Detalles Bibliográficos
Autores principales: Wouters, Elien, de Wit, Nienke M., Vanmol, Jasmine, van der Pol, Susanne M. A., van het Hof, Bert, Sommer, Daniela, Loix, Melanie, Geerts, Dirk, Gustafsson, Jan Ake, Steffensen, Knut R., Vanmierlo, Tim, Bogie, Jeroen F. J., Hendriks, Jerome J. A., de Vries, Helga E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685401/
https://www.ncbi.nlm.nih.gov/pubmed/31417573
http://dx.doi.org/10.3389/fimmu.2019.01811