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Atezolizumab potentiates Tcell-mediated cytotoxicity and coordinates with FAK to suppress cell invasion and motility in PD-L1(+) triple negative breast cancer cells
Immune check point inhibitors targeting programmed cell death protein-1 (PD-1) and its ligand (PD-L1) have shown clinical success in treatment of human malignancies. Triple negative breast cancer (TNBC), which is primarily characterized by high heterogeneity and presence of tumor infiltrating lympho...
Autores principales: | Mohan, Nishant, Hosain, Salman, Zhao, Jun, Shen, Yi, Luo, Xiao, Jiang, Jiangsong, Endo, Yukinori, Wu, Wen Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685513/ https://www.ncbi.nlm.nih.gov/pubmed/31428520 http://dx.doi.org/10.1080/2162402X.2019.1624128 |
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