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Transduction Pattern of AAVs in the Trabecular Meshwork and Anterior-Segment Structures in a Rat Model of Ocular Hypertension

Adeno-associated viruses (AAVs) are the vector of choice for gene therapy in the eye, and self-complementary AAVs (scAAVs), which do not require second-strand DNA synthesis, can be transduced into cells of the trabecular meshwork (TM). The scAAV transduction patterns in the anterior segment of normo...

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Detalles Bibliográficos
Autores principales: Lee, Si Hyung, Sim, Kyeong Sun, Kim, Chan Yun, Park, Tae Kwann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685643/
https://www.ncbi.nlm.nih.gov/pubmed/31406700
http://dx.doi.org/10.1016/j.omtm.2019.06.009

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