The mechanosensitive Piezo1 channel is required for bone formation

Mechanical load of the skeleton system is essential for the development, growth, and maintenance of bone. However, the molecular mechanism by which mechanical stimuli are converted into osteogenesis and bone formation remains unclear. Here we report that Piezo1, a bona fide mechanotransducer that is...

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Detalles Bibliográficos
Autores principales: Sun, Weijia, Chi, Shaopeng, Li, Yuheng, Ling, Shukuan, Tan, Yingjun, Xu, Youjia, Jiang, Fan, Li, Jianwei, Liu, Caizhi, Zhong, Guohui, Cao, Dengchao, Jin, Xiaoyan, Zhao, Dingsheng, Gao, Xingcheng, Liu, Zizhong, Xiao, Bailong, Li, Yingxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685704/
https://www.ncbi.nlm.nih.gov/pubmed/31290742
http://dx.doi.org/10.7554/eLife.47454

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