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Supramolecular trap for catching polyamines in cells as an anti-tumor strategy

Polyamines are essential for the growth of eukaryotic cells and can be dysregulated in tumors. Here we describe a strategy to deplete polyamines through host–guest encapsulation using a peptide-pillar[5]arene conjugate (P1P5A, P1 = RGDSK(N(3))EEEE) as a supramolecular trap. The RGD in the peptide se...

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Detalles Bibliográficos
Autores principales:	Chen, Junyi, Ni, Hanzhi, Meng, Zhao, Wang, Jing, Huang, Xiayang, Dong, Yansheng, Sun, Chao, Zhang, Yadan, Cui, Lei, Li, Jian, Jia, Xueshun, Meng, Qingbin, Li, Chunju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685945/ https://www.ncbi.nlm.nih.gov/pubmed/31391464 http://dx.doi.org/10.1038/s41467-019-11553-7

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