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Real-Time Selective Sequencing with RUBRIC: Read Until with Basecall and Reference-Informed Criteria
The Oxford MinION, the first commercial nanopore sequencer, is also the first to implement molecule-by-molecule real-time selective sequencing or “Read Until”. As DNA transits a MinION nanopore, real-time pore current data can be accessed and analyzed to provide active feedback to that pore. Fragmen...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685950/ https://www.ncbi.nlm.nih.gov/pubmed/31391493 http://dx.doi.org/10.1038/s41598-019-47857-3 |