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Ensilication Improves the Thermal Stability of the Tuberculosis Antigen Ag85b and an Sbi-Ag85b Vaccine Conjugate
There is an urgent need for the development of vaccine thermostabilisation methodologies as the maintenance of a continuous and reliable cold chain remains a major hurdle to the global distribution of safe and effective vaccines. Ensilication, a method that encases proteins in a resistant silica cag...
Autores principales: | Wahid, A. A., Doekhie, A., Sartbaeva, A., van den Elsen, J. M. H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685958/ https://www.ncbi.nlm.nih.gov/pubmed/31391509 http://dx.doi.org/10.1038/s41598-019-47657-9 |
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