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Mimicking natural polymorphism in eIF4E by CRISPR‐Cas9 base editing is associated with resistance to potyviruses

In many crop species, natural variation in eIF4E proteins confers resistance to potyviruses. Gene editing offers new opportunities to transfer genetic resistance to crops that seem to lack natural eIF4E alleles. However, because eIF4E are physiologically important proteins, any introduced modificati...

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Detalles Bibliográficos
Autores principales: Bastet, Anna, Zafirov, Delyan, Giovinazzo, Nathalie, Guyon‐Debast, Anouchka, Nogué, Fabien, Robaglia, Christophe, Gallois, Jean‐Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686125/
https://www.ncbi.nlm.nih.gov/pubmed/30784179
http://dx.doi.org/10.1111/pbi.13096

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