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Foxm1 is a critical driver of TGF‐β‐induced EndMT in endothelial cells through Smad2/3 and binds to the Snail promoter

Endothelial‐to‐mesenchymal transition (EndMT) was first reported in heart development. Recent studies have shown that EndMT also occurs in the progression of cardiac fibrosis. Herein, we demonstrated a critical role of the Forkhead Box M1 (Foxm1) transcription factor in transforming growth factor be...

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Detalles Bibliográficos
Autores principales: Song, Shuai, Zhang, Rui, Cao, Wei, Fang, Guojian, Yu, Yi, Wan, Yi, Wang, Chuanhui, Li, Yigang, Wang, Qunshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686160/
https://www.ncbi.nlm.nih.gov/pubmed/30378114
http://dx.doi.org/10.1002/jcp.27583