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IL‐6/YAP1/β‐catenin signaling is involved in intervertebral disc degeneration
Yes‐associated protein 1 (YAP1) is a transcriptional coactivator and negative regulator of the Hippo pathway. It regulates diverse cellular processes, such as cell proliferation, contact inhibition, and tissue size. However, the role of YAP1 in intervertebral disc degeneration (IDD) remains elusive....
Autores principales: | Chen, Jian, Mei, Zhengfeng, Huang, Bao, Zhang, Xuyang, Liu, Junhui, Shan, Zhi, Wang, Jiasheng, Wang, Xianjun, Zhao, Fengdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686169/ https://www.ncbi.nlm.nih.gov/pubmed/30511395 http://dx.doi.org/10.1002/jcp.27065 |
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