Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity

In two independent microarray studies involving primary airway epithelial cells, the relative gene expression of TMEM178 decreases with the progression of asthma severity. Our manuscript creates a paradigm for future studies dissecting the role of Tmem178 in the pathogenesis of severe asthma.

Detalles Bibliográficos
Autores principales: Patel, Naiya B., Ostilla, Lorena A., Cuervo-Pardo, Lyda, Berdnikovs, Sergejs, Chiarella, Sergio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686220/
https://www.ncbi.nlm.nih.gov/pubmed/31406566
http://dx.doi.org/10.1186/s13601-019-0280-9
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author Patel, Naiya B.
Ostilla, Lorena A.
Cuervo-Pardo, Lyda
Berdnikovs, Sergejs
Chiarella, Sergio E.
author_facet Patel, Naiya B.
Ostilla, Lorena A.
Cuervo-Pardo, Lyda
Berdnikovs, Sergejs
Chiarella, Sergio E.
author_sort Patel, Naiya B.
collection PubMed
description In two independent microarray studies involving primary airway epithelial cells, the relative gene expression of TMEM178 decreases with the progression of asthma severity. Our manuscript creates a paradigm for future studies dissecting the role of Tmem178 in the pathogenesis of severe asthma.
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spelling pubmed-66862202019-08-12 Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity Patel, Naiya B. Ostilla, Lorena A. Cuervo-Pardo, Lyda Berdnikovs, Sergejs Chiarella, Sergio E. Clin Transl Allergy Letter to the Editor In two independent microarray studies involving primary airway epithelial cells, the relative gene expression of TMEM178 decreases with the progression of asthma severity. Our manuscript creates a paradigm for future studies dissecting the role of Tmem178 in the pathogenesis of severe asthma. BioMed Central 2019-08-08 /pmc/articles/PMC6686220/ /pubmed/31406566 http://dx.doi.org/10.1186/s13601-019-0280-9 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Patel, Naiya B.
Ostilla, Lorena A.
Cuervo-Pardo, Lyda
Berdnikovs, Sergejs
Chiarella, Sergio E.
Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity
title Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity
title_full Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity
title_fullStr Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity
title_full_unstemmed Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity
title_short Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity
title_sort gene expression of tmem178, which encodes a negative regulator of nfatc1, decreases with the progression of asthma severity
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686220/
https://www.ncbi.nlm.nih.gov/pubmed/31406566
http://dx.doi.org/10.1186/s13601-019-0280-9
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