Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in Trypanosoma brucei: Intracellular Localization and Properties of the Enzyme

Cytidine deaminase (CDA) is a pyrimidine salvage enzyme that catalyzes cytidine and deoxycytidine hydrolytic deamination to yield uridine and deoxyuridine. Here we report the biochemical characterization of Trypanosoma brucei CDA as an enzyme within the tetrameric class of the CDA family that effici...

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Detalles Bibliográficos
Autores principales: Moro-Bulnes, Ana, Castillo-Acosta, Víctor M., Valente, Maria, Carrero-Lérida, Juana, Pérez-Moreno, Guiomar, Ruiz-Pérez, Luis Miguel, González-Pacanowska, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686228/
https://www.ncbi.nlm.nih.gov/pubmed/31391279
http://dx.doi.org/10.1128/mSphere.00374-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686228/
https://www.ncbi.nlm.nih.gov/pubmed/31391279
http://dx.doi.org/10.1128/mSphere.00374-19

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