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The Aspergillus fumigatus Mismatch Repair MSH2 Homolog Is Important for Virulence and Azole Resistance

The genetic stability of every living organism depends on accurate DNA replication and repair systems. Here, we investigated the Aspergillus fumigatus MSH2 mismatch repair (MMR) gene MshA and how it impacts virulence and the evolution of azole resistance. We examined mshA gene variation in 62 enviro...

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Detalles Bibliográficos
Autores principales: dos Reis, Thaila Fernanda, Silva, Lilian Pereira, de Castro, Patrícia Alves, do Carmo, Rafaela Andrade, Marini, Marjorie Mendes, da Silveira, José Franco, Ferreira, Beatriz Henriques, Rodrigues, Fernando, Lind, Abigail Lee, Rokas, Antonis, Goldman, Gustavo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686229/
https://www.ncbi.nlm.nih.gov/pubmed/31391280
http://dx.doi.org/10.1128/mSphere.00416-19