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The Effect of Symptom Duration on Outcomes After Fusion for Degenerative Spondylolisthesis

STUDY DESIGN: Longitudinal comparative cohort. OBJECTIVES: To determine if the duration of symptoms in patients with degenerative spondylolisthesis affects postoperative outcomes after 1- or 2-level decompression and fusion. METHODS: Patients undergoing primary surgery for grade 1 degenerative spond...

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Autores principales: Fleming, John, Glassman, Steven D., Miller, Adam, Dimar, John R., Djurasovic, Mladen, Carreon, Leah Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686385/
https://www.ncbi.nlm.nih.gov/pubmed/31431870
http://dx.doi.org/10.1177/2192568218804557
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author Fleming, John
Glassman, Steven D.
Miller, Adam
Dimar, John R.
Djurasovic, Mladen
Carreon, Leah Y.
author_facet Fleming, John
Glassman, Steven D.
Miller, Adam
Dimar, John R.
Djurasovic, Mladen
Carreon, Leah Y.
author_sort Fleming, John
collection PubMed
description STUDY DESIGN: Longitudinal comparative cohort. OBJECTIVES: To determine if the duration of symptoms in patients with degenerative spondylolisthesis affects postoperative outcomes after 1- or 2-level decompression and fusion. METHODS: Patients undergoing primary surgery for grade 1 degenerative spondylolisthesis at a single Quality Outcomes Database (QOD) participating site were identified. Demographic, surgical and patient-reported outcomes (PROs) data, including baseline and 12-month postoperative Oswestry Disability Index (ODI), back pain (BP, 0-10), leg pain (LP, 0-10), and EuroQOL-5D (EQ-5D) scores were collected. Individual medical records were reviewed for data on duration of symptoms prior to surgery. Patients were stratified into 3 cohorts—those with preoperative symptom duration of less than 1 year, 1 to 2 years, or greater than 2 years. RESULTS: Complete data was available in 123 patients. Significant improvement in ODI, BP, and LP scores were observed in all groups. At 12-month follow-up improvement in ODI, BP, or LP was similar among the cohorts; with a trend toward significance with better improvement in LP scores in patients with a symptom duration of less than 1 year to those with symptom duration greater than 2 years (P = .058). CONCLUSIONS: The duration of symptoms up to 2 years prior to surgery may not be a useful predictor of improvement of back pain or disability scores in patients with spondylolisthesis requiring decompression and fusion. Although there was a positive trend for improvement in leg pain for those with a shorter duration of symptoms, this did not reach statistical significance in our study.
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spelling pubmed-66863852019-08-20 The Effect of Symptom Duration on Outcomes After Fusion for Degenerative Spondylolisthesis Fleming, John Glassman, Steven D. Miller, Adam Dimar, John R. Djurasovic, Mladen Carreon, Leah Y. Global Spine J Original Articles STUDY DESIGN: Longitudinal comparative cohort. OBJECTIVES: To determine if the duration of symptoms in patients with degenerative spondylolisthesis affects postoperative outcomes after 1- or 2-level decompression and fusion. METHODS: Patients undergoing primary surgery for grade 1 degenerative spondylolisthesis at a single Quality Outcomes Database (QOD) participating site were identified. Demographic, surgical and patient-reported outcomes (PROs) data, including baseline and 12-month postoperative Oswestry Disability Index (ODI), back pain (BP, 0-10), leg pain (LP, 0-10), and EuroQOL-5D (EQ-5D) scores were collected. Individual medical records were reviewed for data on duration of symptoms prior to surgery. Patients were stratified into 3 cohorts—those with preoperative symptom duration of less than 1 year, 1 to 2 years, or greater than 2 years. RESULTS: Complete data was available in 123 patients. Significant improvement in ODI, BP, and LP scores were observed in all groups. At 12-month follow-up improvement in ODI, BP, or LP was similar among the cohorts; with a trend toward significance with better improvement in LP scores in patients with a symptom duration of less than 1 year to those with symptom duration greater than 2 years (P = .058). CONCLUSIONS: The duration of symptoms up to 2 years prior to surgery may not be a useful predictor of improvement of back pain or disability scores in patients with spondylolisthesis requiring decompression and fusion. Although there was a positive trend for improvement in leg pain for those with a shorter duration of symptoms, this did not reach statistical significance in our study. SAGE Publications 2018-10-09 2019-08 /pmc/articles/PMC6686385/ /pubmed/31431870 http://dx.doi.org/10.1177/2192568218804557 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (http://www.creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Fleming, John
Glassman, Steven D.
Miller, Adam
Dimar, John R.
Djurasovic, Mladen
Carreon, Leah Y.
The Effect of Symptom Duration on Outcomes After Fusion for Degenerative Spondylolisthesis
title The Effect of Symptom Duration on Outcomes After Fusion for Degenerative Spondylolisthesis
title_full The Effect of Symptom Duration on Outcomes After Fusion for Degenerative Spondylolisthesis
title_fullStr The Effect of Symptom Duration on Outcomes After Fusion for Degenerative Spondylolisthesis
title_full_unstemmed The Effect of Symptom Duration on Outcomes After Fusion for Degenerative Spondylolisthesis
title_short The Effect of Symptom Duration on Outcomes After Fusion for Degenerative Spondylolisthesis
title_sort effect of symptom duration on outcomes after fusion for degenerative spondylolisthesis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686385/
https://www.ncbi.nlm.nih.gov/pubmed/31431870
http://dx.doi.org/10.1177/2192568218804557
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