Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson’s disease and multiple system atrophy

BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disorder whose diagnosis is often challenging because symptoms may overlap with neurodegenerative parkinsonisms. PD is characterized by intraneuronal accumulation of abnormal α-synuclein in brainstem while neurodegenerative parkinsonisms mi...

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Detalles Bibliográficos
Autores principales: De Luca, Chiara Maria Giulia, Elia, Antonio Emanuele, Portaleone, Sara Maria, Cazzaniga, Federico Angelo, Rossi, Martina, Bistaffa, Edoardo, De Cecco, Elena, Narkiewicz, Joanna, Salzano, Giulia, Carletta, Olga, Romito, Luigi, Devigili, Grazia, Soliveri, Paola, Tiraboschi, Pietro, Legname, Giuseppe, Tagliavini, Fabrizio, Eleopra, Roberto, Giaccone, Giorgio, Moda, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686411/
https://www.ncbi.nlm.nih.gov/pubmed/31406572
http://dx.doi.org/10.1186/s40035-019-0164-x

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