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Targeting CYP4A attenuates hepatic steatosis in a novel multicellular organotypic liver model
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) begins as simple hepatic steatosis, but further progress to chronic liver diseases results in severe liver damage and hepatic failure. However, therapeutic options are scarce due to the lack of reliable human in vitro liver models for understandi...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686528/ https://www.ncbi.nlm.nih.gov/pubmed/31406506 http://dx.doi.org/10.1186/s13036-019-0198-8 |