Dynamic and unpredictable changes in mutant allele fractions of BRAF and NRAS during visceral progression of cutaneous malignant melanoma

BACKGROUND: Data indicate that primary cutaneous melanomas are characterized by clonal heterogeneity associated with oncogenic drivers. Less data are available on the clonal changes occurring during melanoma progression. We therefore wished to analyse these changes in skin melanomas in common sites...

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Detalles Bibliográficos
Autores principales: Doma, V., Kárpáthy, S., Rásó, E., Barbai, T., Tímár, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686548/
https://www.ncbi.nlm.nih.gov/pubmed/31391014
http://dx.doi.org/10.1186/s12885-019-5990-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686548/
https://www.ncbi.nlm.nih.gov/pubmed/31391014
http://dx.doi.org/10.1186/s12885-019-5990-9

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