Efficacy of administered mesenchymal stem cells in the initiation and co‐ordination of repair processes by resident disc cells in an ovine (Ovis aries) large destabilizing lesion model of experimental disc degeneration

BACKGROUND: Forty percent of low back pain cases are due to intervertebral disc degeneration (IVDD), with mesenchymal stem cells (MSCs) a reported treatment. We utilized an ovine IVDD model and intradiscal heterologous MSCs to determine therapeutic efficacy at different stages of IVDD. METHODOLOGY:...

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Detalles Bibliográficos
Autores principales: Shu, Cindy C., Dart, Andrew, Bell, Robin, Dart, Christina, Clarke, Elizabeth, Smith, Margaret M., Little, Christopher B., Melrose, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686814/
https://www.ncbi.nlm.nih.gov/pubmed/31463452
http://dx.doi.org/10.1002/jsp2.1037

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