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Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits

Identifying the regulatory mechanisms of genome-wide association study (GWAS) loci affecting adipose tissue has been restricted due to limited characterization of adipose transcriptional regulatory elements. We profiled chromatin accessibility in three frozen human subcutaneous adipose tissue needle...

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Detalles Bibliográficos
Autores principales: Cannon, Maren E., Currin, Kevin W., Young, Kristin L., Perrin, Hannah J., Vadlamudi, Swarooparani, Safi, Alexias, Song, Lingyun, Wu, Ying, Wabitsch, Martin, Laakso, Markku, Crawford, Gregory E., Mohlke, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686932/
https://www.ncbi.nlm.nih.gov/pubmed/31186305
http://dx.doi.org/10.1534/g3.119.400294

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