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Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits
Identifying the regulatory mechanisms of genome-wide association study (GWAS) loci affecting adipose tissue has been restricted due to limited characterization of adipose transcriptional regulatory elements. We profiled chromatin accessibility in three frozen human subcutaneous adipose tissue needle...
Autores principales: | Cannon, Maren E., Currin, Kevin W., Young, Kristin L., Perrin, Hannah J., Vadlamudi, Swarooparani, Safi, Alexias, Song, Lingyun, Wu, Ying, Wabitsch, Martin, Laakso, Markku, Crawford, Gregory E., Mohlke, Karen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686932/ https://www.ncbi.nlm.nih.gov/pubmed/31186305 http://dx.doi.org/10.1534/g3.119.400294 |
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