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Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia

BACKGROUND: Hypertriglyceridemia is associated with increased cardiovascular risk and may be caused by impaired lipoprotein clearance. Angiopoietin-like protein 3 (ANGPTL3) inhibits lipoprotein lipase activity, increasing triglycerides and other lipids. Evinacumab, an ANGPTL3 inhibitor, reduced trig...

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Detalles Bibliográficos
Autores principales:	Ahmad, Zahid, Banerjee, Poulabi, Hamon, Sara, Chan, Kuo-Chen, Bouzelmat, Aurelie, Sasiela, William J., Pordy, Robert, Mellis, Scott, Dansky, Hayes, Gipe, Daniel A., Dunbar, Richard L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2019
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686956/ https://www.ncbi.nlm.nih.gov/pubmed/31242752 http://dx.doi.org/10.1161/CIRCULATIONAHA.118.039107

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