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P450 Monooxygenases Enable Rapid Late‐Stage Diversification of Natural Products via C−H Bond Activation
The biological potency of natural products has been exploited for decades. Their inherent structural complexity and natural diversity might hold the key to efficiently address the urgent need for the development of novel pharmaceuticals. At the same time, it is that very complexity, which impedes ne...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686969/ https://www.ncbi.nlm.nih.gov/pubmed/31423290 http://dx.doi.org/10.1002/cctc.201801829 |