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Prevalence of impaired fasting glucose, type 2 diabetes and associated risk factors in undiagnosed Chinese rural population: the Henan Rural Cohort Study
OBJECTIVE: This study estimated the burden and characterised the risk factors associated with diabetes and impaired fasting glucose (IFG) in an undiagnosed rural population. DESIGN: Data for 36 960 participants from the Henan Rural Cohort baseline with undiagnosed diabetes were analysed. X(2) test a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686996/ https://www.ncbi.nlm.nih.gov/pubmed/31383706 http://dx.doi.org/10.1136/bmjopen-2019-029628 |
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author | Abdulai, Tanko Li, Yuqian Zhang, Haiqing Tu, Runqi Liu, Xiaotian Zhang, Liying Dong, Xiaokang Li, Ruiying Wang, Yuming Wang, Chongjian |
author_facet | Abdulai, Tanko Li, Yuqian Zhang, Haiqing Tu, Runqi Liu, Xiaotian Zhang, Liying Dong, Xiaokang Li, Ruiying Wang, Yuming Wang, Chongjian |
author_sort | Abdulai, Tanko |
collection | PubMed |
description | OBJECTIVE: This study estimated the burden and characterised the risk factors associated with diabetes and impaired fasting glucose (IFG) in an undiagnosed rural population. DESIGN: Data for 36 960 participants from the Henan Rural Cohort baseline with undiagnosed diabetes were analysed. X(2) test and multivariate logistic regression analyses were performed to test for association between risk factors and diabetes and IFG. RESULTS: Women constituted 60.30% of the study participants, mean age of participants was 55.32±12.18 years, risk factors for diabetes and IFG were prevalent (75% dyslipidaemia, 57% overweight/obese, 50% central obesity and 18% metabolic syndrome). The prevalence of diabetes and IFG was 4.19% and 7.22%, respectively. Having a metabolic syndrome (adjusted OR (aOR) 4.7, 95% CI 4.27 to 5.33), dyslipidaemia (aOR 2.76, 95% CI 2.31 to 3.21), centrally obese (aOR 2.38, 95% CI 2.11 to 2.70), being overweight/obese (aOR 1.66, 95% CI 1.45 to 1.79) and a family history of diabetes (aOR 1.50, 95% CI 1.15 to 1.92) were associated with diabetes. These factors were also associated with IFG. Intake of high salt diet (aOR 1.16, 95% CI 1.02 to 1.32) and smoking (aOR 1.22, 95% CI 1.02 to 1.47; significant in men) were also associated with diabetes. Engaging in moderate physical activity (aOR 0.94, 95% CI 0.89 to 0.98) was noted to be negatively associated with diabetes. CONCLUSION: Diabetes and IFG remain prevalent in Chinese population with obesity and dyslipidaemia being some of the most significant predictors. Regular physical activity and consumption of fruits and vegetables may be beneficial in keeping blood glucose level low. TRIAL REGISTRATION NUMBER: ChiCTR-OOC-15006699 |
format | Online Article Text |
id | pubmed-6686996 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-66869962019-08-23 Prevalence of impaired fasting glucose, type 2 diabetes and associated risk factors in undiagnosed Chinese rural population: the Henan Rural Cohort Study Abdulai, Tanko Li, Yuqian Zhang, Haiqing Tu, Runqi Liu, Xiaotian Zhang, Liying Dong, Xiaokang Li, Ruiying Wang, Yuming Wang, Chongjian BMJ Open Epidemiology OBJECTIVE: This study estimated the burden and characterised the risk factors associated with diabetes and impaired fasting glucose (IFG) in an undiagnosed rural population. DESIGN: Data for 36 960 participants from the Henan Rural Cohort baseline with undiagnosed diabetes were analysed. X(2) test and multivariate logistic regression analyses were performed to test for association between risk factors and diabetes and IFG. RESULTS: Women constituted 60.30% of the study participants, mean age of participants was 55.32±12.18 years, risk factors for diabetes and IFG were prevalent (75% dyslipidaemia, 57% overweight/obese, 50% central obesity and 18% metabolic syndrome). The prevalence of diabetes and IFG was 4.19% and 7.22%, respectively. Having a metabolic syndrome (adjusted OR (aOR) 4.7, 95% CI 4.27 to 5.33), dyslipidaemia (aOR 2.76, 95% CI 2.31 to 3.21), centrally obese (aOR 2.38, 95% CI 2.11 to 2.70), being overweight/obese (aOR 1.66, 95% CI 1.45 to 1.79) and a family history of diabetes (aOR 1.50, 95% CI 1.15 to 1.92) were associated with diabetes. These factors were also associated with IFG. Intake of high salt diet (aOR 1.16, 95% CI 1.02 to 1.32) and smoking (aOR 1.22, 95% CI 1.02 to 1.47; significant in men) were also associated with diabetes. Engaging in moderate physical activity (aOR 0.94, 95% CI 0.89 to 0.98) was noted to be negatively associated with diabetes. CONCLUSION: Diabetes and IFG remain prevalent in Chinese population with obesity and dyslipidaemia being some of the most significant predictors. Regular physical activity and consumption of fruits and vegetables may be beneficial in keeping blood glucose level low. TRIAL REGISTRATION NUMBER: ChiCTR-OOC-15006699 BMJ Publishing Group 2019-08-05 /pmc/articles/PMC6686996/ /pubmed/31383706 http://dx.doi.org/10.1136/bmjopen-2019-029628 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Epidemiology Abdulai, Tanko Li, Yuqian Zhang, Haiqing Tu, Runqi Liu, Xiaotian Zhang, Liying Dong, Xiaokang Li, Ruiying Wang, Yuming Wang, Chongjian Prevalence of impaired fasting glucose, type 2 diabetes and associated risk factors in undiagnosed Chinese rural population: the Henan Rural Cohort Study |
title | Prevalence of impaired fasting glucose, type 2 diabetes and associated risk factors in undiagnosed Chinese rural population: the Henan Rural Cohort Study |
title_full | Prevalence of impaired fasting glucose, type 2 diabetes and associated risk factors in undiagnosed Chinese rural population: the Henan Rural Cohort Study |
title_fullStr | Prevalence of impaired fasting glucose, type 2 diabetes and associated risk factors in undiagnosed Chinese rural population: the Henan Rural Cohort Study |
title_full_unstemmed | Prevalence of impaired fasting glucose, type 2 diabetes and associated risk factors in undiagnosed Chinese rural population: the Henan Rural Cohort Study |
title_short | Prevalence of impaired fasting glucose, type 2 diabetes and associated risk factors in undiagnosed Chinese rural population: the Henan Rural Cohort Study |
title_sort | prevalence of impaired fasting glucose, type 2 diabetes and associated risk factors in undiagnosed chinese rural population: the henan rural cohort study |
topic | Epidemiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686996/ https://www.ncbi.nlm.nih.gov/pubmed/31383706 http://dx.doi.org/10.1136/bmjopen-2019-029628 |
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