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Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE)

OBJECTIVE: Systemic lupus erythematosus (SLE) features high frequency of cardiovascular disease (CVD) and fluctuating complement levels. The clinical trial Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) aimed to evaluate whether atorvastatin treatment reduced the progression of...

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Detalles Bibliográficos
Autores principales:	Mulvihill, Evan, Ardoin, Stacy, Thompson, Susan D, Zhou, Bi, Yu, Gakit Richard, King, Emily, Singer, Nora, Levy, D M, Brunner, Hermine, Wu, Yee Ling, Nagaraja, Haikady N, Schanberg, Laura Eve, Yu, Chack-Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Childhood Lupus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687033/ https://www.ncbi.nlm.nih.gov/pubmed/31448126 http://dx.doi.org/10.1136/lupus-2019-000333

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