A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer

Lobectomy is considered the standard strategy for early-stage non-small cell lung cancer (NSCLC). However, sublobar resection for NSCLC has recently received increased attention. The objective of this study was to compare 5-year survival, recurrence-free survival, postoperative mortality, and postop...

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Autores principales: Lim, Tae Yoon, Park, Samina, Kang, Chang Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Thoracic and Cardiovascular Surgery 2019
Materias:
Collective of Current Review, Lecture
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687045/
https://www.ncbi.nlm.nih.gov/pubmed/31404409
http://dx.doi.org/10.5090/kjtcs.2019.52.4.195
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author Lim, Tae Yoon
Park, Samina
Kang, Chang Hyun
author_facet Lim, Tae Yoon
Park, Samina
Kang, Chang Hyun
author_sort Lim, Tae Yoon
collection PubMed
description Lobectomy is considered the standard strategy for early-stage non-small cell lung cancer (NSCLC). However, sublobar resection for NSCLC has recently received increased attention. The objective of this study was to compare 5-year survival, recurrence-free survival, postoperative mortality, and postoperative morbidities in patients who received segmentectomy versus those who received lobectomy through a meta-analysis. Sixteen studies were included and the combined hazard ratios or odds ratios were calculated. The results revealed that the 5-year survival rate after segmentectomy was comparable to that of lobectomy for stage IA NSCLC. However, segmentectomy for stage I NSCLC had lower rates of postoperative mortality and morbidities than lobectomy.
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spelling pubmed-66870452019-08-09 A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer Lim, Tae Yoon Park, Samina Kang, Chang Hyun Korean J Thorac Cardiovasc Surg Collective of Current Review, Lecture Lobectomy is considered the standard strategy for early-stage non-small cell lung cancer (NSCLC). However, sublobar resection for NSCLC has recently received increased attention. The objective of this study was to compare 5-year survival, recurrence-free survival, postoperative mortality, and postoperative morbidities in patients who received segmentectomy versus those who received lobectomy through a meta-analysis. Sixteen studies were included and the combined hazard ratios or odds ratios were calculated. The results revealed that the 5-year survival rate after segmentectomy was comparable to that of lobectomy for stage IA NSCLC. However, segmentectomy for stage I NSCLC had lower rates of postoperative mortality and morbidities than lobectomy. The Korean Society for Thoracic and Cardiovascular Surgery 2019-08 2019-08-05 /pmc/articles/PMC6687045/ /pubmed/31404409 http://dx.doi.org/10.5090/kjtcs.2019.52.4.195 Text en Copyright © 2019 by The Korean Society for Thoracic and Cardiovascular Surgery. All rights Reserved. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Collective of Current Review, Lecture
Lim, Tae Yoon
Park, Samina
Kang, Chang Hyun
A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer
title A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer
title_full A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer
title_fullStr A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer
title_full_unstemmed A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer
title_short A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer
title_sort meta-analysis comparing lobectomy versus segmentectomy in stage i non-small cell lung cancer
topic Collective of Current Review, Lecture
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687045/
https://www.ncbi.nlm.nih.gov/pubmed/31404409
http://dx.doi.org/10.5090/kjtcs.2019.52.4.195
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